Pharmaceutical Tablets

Uses / Indications

This combination is commonly used for:

• Relief from abdominal pain and cramps

• Irritable Bowel Syndrome (IBS) related spasms

• Menstrual pain (dysmenorrhea)

• Colic pain (stomach pain due to spasm)

• General antispasmodic and analgesic relief

How It Works

• Dicyclomine Hydrochloride: An antispasmodic that relaxes smooth muscles of the stomach and intestine, reducing cramps.

• Paracetamol: A mild analgesic and antipyretic that reduces pain and fever.

Together, they provide fast relief from pain due to abdominal cramps.

Dosage (General Guidance – must be prescribed by doctor)

• Typically: 1 tablet 2–3 times daily, depending on severity.

• Dosage varies for children and adults.

• Should be taken with water, after meals to reduce gastric irritation.

Side Effects

Common:

• Dry mouth, dizziness

• Nausea, constipation

• Drowsiness

Serious (rare):

• Allergic reaction (rash, swelling, breathing difficulty)

• Blurred vision

• Increased heart rate

• Hepatotoxicity (liver damage risk with long-term or high-dose Paracetamol)

Warnings & Precautions

• Prescription-only medicine (Rx).

• Avoid in patients with:

  • Severe liver disease

  • Glaucoma

  • Enlarged prostate or urinary retention

• Use with caution in pregnancy and breastfeeding (only under doctor’s advice).

• Avoid alcohol (increases liver toxicity with Paracetamol).

Storage

• Store in a cool, dry place away from direct light.

• Keep away from children.

Glimepiride is indicated for the treatment of type 2 diabetes mellitus, when diet, physical exercise and weight reduction alone are not adequate. The basis for successful treatment of diabetes is a good diet, regular physical activity, as well as routine checks of blood and urine.

Uses / Indications

MEF-SPAS is used for the treatment of pain associated with abdominal cramps and spasms, such as:

• Menstrual pain (dysmenorrhea)

• Abdominal colic (intestinal/stomach cramps)

• Irritable Bowel Syndrome (IBS) spasms

• Post-surgical abdominal pain

• Other spasmodic and inflammatory pain conditions

How It Works

• Mefenamic Acid: A non-steroidal anti-inflammatory drug (NSAID) that reduces pain, inflammation, and fever.

• Dicyclomine Hydrochloride: An antispasmodic that relaxes smooth muscles of the gastrointestinal tract, reducing cramps and spasms.

Together, they provide dual relief — pain reduction + muscle relaxation.

Dosage (General Guidance – must be doctor prescribed)

• Typically: 1 tablet 2–3 times a day after meals.

• Dose depends on severity and patient’s condition.

• Not recommended for children unless prescribed by a doctor.

Side Effects

Common:

• Nausea, vomiting

• Drowsiness, dizziness

• Dry mouth, constipation

• Stomach upset

Serious (rare):

• Stomach ulcers or bleeding (from Mefenamic Acid, if used long-term)

• Allergic reaction (rash, itching, swelling, breathing difficulty)

• Blurred vision, fast heartbeat (from Dicyclomine in sensitive patients)

Warnings & Precautions

• Prescription-only medicine (Rx)

• Should be used with caution in:

  • Patients with gastric ulcers, kidney disease, or liver problems

  • Patients with asthma or respiratory issues

• Not recommended in pregnancy & breastfeeding unless clearly prescribed

• Avoid alcohol (increases stomach irritation and risk of bleeding)

• Do not combine with other NSAIDs (like Ibuprofen, Aspirin)

Storage

• Store in a cool, dry place, away from sunlight.

• Keep out of reach of children.

Active Ingredient

• Tapentadol Hydrochloride 100 mg per tablet

Indications (Medical Use)

Tapentadol is a centrally acting analgesic (pain reliever) used for:

• Moderate to severe acute pain

• Chronic pain management (including neuropathic pain)

Mechanism of Action

• Dual action:

  1. μ-opioid receptor agonist (like opioids → reduces pain perception)

  2. Norepinephrine reuptake inhibitor (NRI) (enhances pain suppression in spinal pathways)

Dosage (General Information)

(Exact dosage must be prescribed by a doctor)

• Typical starting dose: 50–100 mg every 4–6 hours as needed

• Max daily dose: Usually not exceeding 600 mg/day for acute pain

Side Effects

Common:

• Nausea, vomiting

• Dizziness, drowsiness

• Constipation

• Headache

Serious:

• Respiratory depression (slowed breathing)

• Risk of dependence or misuse (opioid-like properties)

• Seizures (rare)

Precautions & Warnings

• Controlled Substance: Potential for addiction, misuse, and dependence

• Avoid alcohol and other CNS depressants

• Not recommended for patients with severe respiratory depression

• Use caution in kidney or liver impairment

• Avoid driving or operating heavy machinery

Tapentadol is used for:

• Moderate to severe acute pain (after surgery, trauma, injury)

• Chronic pain conditions (like musculoskeletal pain, lower back pain)

• Neuropathic pain (nerve-related pain, such as diabetic neuropathy)

Tapentadol works through dual action:

1. Opioid receptor agonist – reduces perception of pain.

2. Norepinephrine reuptake inhibitor (NRI) – enhances the natural suppression of pain in the central nervous system.

• Usual starting dose: 50–100 mg every 4–6 hours as needed

• Maximum dose for acute pain: 600 mg/day

• For chronic pain: 500 mg/day
  (Exact dosing depends on medical condition, severity of pain, and patient tolerance)

Common:

• Nausea, vomiting

• Dizziness, drowsiness, headache

• Constipation

Serious:

• Respiratory depression (slowed breathing)

• Dependence, tolerance, or misuse (opioid-like properties)

• Seizures (rare but possible)

• Prescription-only medicine (Rx)

• Risk of addiction and misuse

• Avoid alcohol and sedatives (may increase drowsiness or breathing issues)

• Use cautiously in patients with liver/kidney impairment

• Not suitable for patients with severe respiratory problems

• Should not be stopped suddenly after long-term use (to avoid withdrawal symptoms)

• Store in a cool, dry place, away from sunlight.

• Keep out of reach of children.

Tapentadol is a medication used to relieve moderate to severe pain. It's available in tablet form, and the 100 mg dosage is one of the strengths in which it is commonly prescribed.